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While you are pregnant, your body goes through a myriad of changes. Although, some of these changes are good, others can lead to complications and make your difficult pregnancy. In these cases, you have to turn for relief medications. However, you need to know which medications are safe to use during pregnancy. One such drug is Cymbalta or Duloxetine. Read our post below to learn more about the safety of using Cymbalta while pregnant.
What is Cymbalta (Duloxetine)?
Cymbalta is prescription medicine for depression and general anxiety disorder (GAD). It is also used for the treatment of peripheral neuropathy, that is neuropathic pain that patients with diabetes often experience. Other conditions that Cymbalta treats are back pain, arthritis and fibromyalgia (muscle pain and stiffness with problems of fatigue and sleep). Cymbalta (duloxetine) falls under the classification of drugs called selective serotonin reuptake inhibitors and norepinephrine (SNRI). SNRIs such as duloxetine work to balance the amount of noradrenaline and serotonin (neurotransmitters) in brain.
Cymbalta is the trade name of the drug, while its generic name is duloxetine. It 'available in delayed-release capsules. A delayed release refers to a drug that breaks down in the intestines. Cymbalta dosage is different for each of the conditions it is. The dosage may also depend on the individual health status [1].
And 'safe to use Cymbalta during pregnancy?
Cymbalta is not considered safe to use during pregnancy.
The use of Cymbalta during pregnancy can damage the health of the fetus. If you use Cymbalta during the last trimester of pregnancy, there is a chance that the baby will develop some withdrawal symptoms. These symptoms may be feeding difficulties, seizures, breathing problems, irritability and muscle stiffness [2].
is requiredMore research to study the effects of duloxetine during pregnancy. But existing studies show that the use of duloxetine can cause maternal and fetal damage. Your doctor may prescribe Cymbalta during pregnancy only if necessary and after evaluating the drug's use to you against its harm to you and your unborn baby [3].
If you receive treatment for a condition treatable with the use Cymbalta, take precautions. If you are planning pregnancy, it is vital to inform your doctor before using Cymbalta. The use of duloxetine may not be safe for lactating. But there are not enough data available yet.
The use of duloxetine during pregnancy can increase the risk of spontaneous abortions [4].
[ Read: Flu During Pregnancy ]
side effects of Cymbalta during pregnancy:
The use of Cymbalta during pregnancy can produce many side effects
- Consult your doctor if you experience. The following side effects with Cymbalta use:
- Nausea
- Dizziness (may be caused by changes in dosage, initial use)
- Dry mouth
- Constipation
- Diarrhea
- Fatigue
- Drowsiness
- Weakness
- Decreased Appetite
- muscle pain
- Stomach pain
- Low libido
- decreased sexual ability
- frequent urination
- Problems urinating
- Heartburn
- Tremors
- Confusion
- High blood pressure
Use Cymbalta in pregnancy may also cause some serious side effects. In the event that you experience the following symptoms with the use of Cymbalta, seek medical advice immediately [5].
Severe Effects:
- swollen abdomen
- flu-like symptoms (fever, chills, muscle aches)
- irregular heartbeat
- breathing problems
- difficulty swallowing
- swelling of the feet, hands, tongue, throat, and face
- Mouth sores
- Rash
- Hives
- Hoarseness
- Extreme fatigue
- Itching
- bruising
- The urine color variations
- yellow tinge in the eyes or the face
- Blood in I
- pain, redness or swelling of the eyes
- Changes in the quality of vision, blurred vision
- Seizures
- serotonin toxicity
You may also experience other adverse effects with the use Cymbalta. Whenever you feel discomfort, pain or persistent symptoms after using Cymbalta, talk to your doctor [6].
[ Read: Constipation During Pregnancy ]
Drug Interactions:
If you use Cymbalta together with any other medicines, you should disclose this to your doctor during your initial consultation. Cymbalta can interact with certain medications and cause some side effects or health problems. drug interactions also reduce the effectiveness of one or more drugs that you are using at the same time. [7]
List of medications that may interact with duloxetine:
- anti-inflammatory drugs (NSAIDs) such as aspirin, naproxen or ibuprofen. NSAIDs are used to treat pain or inflammation. Aspirin use alongside Cymbalta can cause bleeding.
- inhibitors of monoamine oxidase (MAO), such as linezolid, tranylcypromine, rasagiline, salicylate, methylene blue, procarbazine and others. MAO are a type of antidepressant. If you plan to use Cymbalta, do not use MAIOs two weeks before the first dose. In addition, wait at least five days after the last dose of Cymbalta before taking any MAIOs.
- If you take other drugs that increase serotonin, then you may suffer from serotonin toxicity. Examples include antidepressants such as fluoxetine or venlafaxine.
- blood thinners or anticoagulants, such as warfarin.
- Some tranquilizers such as zolpidem.
- herbal products containing St. John's wort.
- Antihistamines such as diphenhydramine.
- Cymbalta may reduce the effectiveness of some medications such as tricyclic antidepressants, antipsychotics and anti-arrhythmic drugs (to normalize the heart rhythm).
- quinolone antibiotics like ciprofloxacin may reduce the effectiveness of Cymbalta.
[ Read: Cymbalta During Breastfeeding ]
Use Of antidepressants during pregnancy:
The doctor may recommend the use of antidepressants during pregnancy depending on your health and the need for treatment
A word of caution :.
- Depression during pregnancy is harmful to maternal and fetal health. Some doctors may prescribe the use of antidepressants to keep the symptoms of depression under control. Although there are risks associated with the use of antidepressants during pregnancy, certain drugs such as SNRIs (like Cymbalta) are known to have minimal side effects. There are also other antidepressant drugs that contain low risk to the health of the fetus.
- If you suffer from mild depression, it is likely that your doctor will ask you to stop using any antidepressant drug.
- The doctor is likely to continue your prescription for Cymbalta or any other antidepressant in case you suffer from recurrent depression or suicidal thoughts.
- If you suffer from depression, it is best to complete the treatment for depression before planning pregnancy. If the depression continues with the pregnancy, weigh all the treatment options and their risks and benefits.
Remember, all antidepressants, such as Cymbalta contain risks to the health of the fetus. So, make an informed decision about any drug use during pregnancy.
Have you taken antidepressants during pregnancy? Have you had any side effects with its use? Tell us below
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